Superstar swimmer, American Michael Phelps, finished fourth in the 400-meter individual medley, while teammate Ryan Lochte won the gold.
Phelps has won 16 Olympic medals and needs three more to break the all-time record.
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In the men's archery semifinals, the U.S. shocked South Korea and moved into the gold medal match against Italy. South Korea had won the last three Olympic gold medals.
And in men's under-60 kilogram judo, Russia's Arsen Galstyan upset the top two seeds, including two-time world champion Rishod Sobirov of Uzbekistan.
But the heavily favored U.S. women's basketball team met expectations, defeating Croatia, 81-56. The U.S. has won four straight Olympic gold medals and 34 consecutive Olympic games.
Away from the action, South Korean swimmer Park Tae-Hwan was reinstated as a finalist for Saturday's 400-meter race after being disqualified for what was ruled a false start in a qualifying race. Park was the 2008 Olympic champion in that event.
Albanian weightlifter, Hysen Pulaku, became the first athlete ejected from the London Olympics after testing positive for steroids.
"On the doping of course, it is always a sad day when a cheating athlete is caught," said Mark Adams of the International Olympic Committee, commenting on the ejection. "I hope there will be no more, but the message we get out of this is that we will catch you. There are going to be 5,000 tests during this games and all the medalists will be tested so no one can think they will get away and that's a very good, clear message to send. It's disappointing."
More than 10,000 athletes in 26 sports are competing in the London Oympics, which run through August 12.
